Renoprotective effects of telmisartan in the 5/6 nephrectomised rats
نویسندگان
چکیده
منابع مشابه
Renoprotective effects of telmisartan after unilateral renal ablation in rats
PURPOSE The renoprotective function of the angiotensin II type 1 receptor blocker (ARB) is well-known in various studies, including the animal model of renal failure. However, detailed temporal changes of pathological and molecular findings after unilateral nephrectomy are not fully understood. The main purpose of this study was to clarify the renoprotective effects and pathological changes ind...
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Diabetic nephropathy occurs in approximately one-third of all people with diabetes and is the leading cause of renal failure in developed and developing countries. Angiotensin II plays a potent role in the initiation and progression of diabetic nephropathy by increasing glmoerular pressure and glmoerular selectivity as well as activation of fibrosis and cellular growth in the kidney. Thus, agen...
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ژورنال
عنوان ژورنال: Journal of the Renin-Angiotensin-Aldosterone System
سال: 2007
ISSN: 1470-3203,1752-8976
DOI: 10.3317/jraas.2007.017